Molecular Biology Basics: Unlocking Life’S Code!

DNA replication, DNA Transcription, DNA Translation.

What you’ll learn
History of DNA
DNA structure and function
DNA Epigenetic Mechanisms of Gene Expression
DNA replication
DNA damage repair mechanisms
DNA Transcription
Post-Transcriptional Modifications
DNA Translation
Post-Translational Modifications
Gene regulation mechanisms

Requirements
Basic understanding of Biology.

Description
Introduction To DNAIntroduction to the courseDNA is the genetic material ExperimentsGriffith’s Transformation Experiment (1928).Avery, MacLeod and McCarty’s Experiment (1944).Hershey and Chase’s Experiment (1952).DNA structure and functionDNA structure.DNA role and function.DNA organization inside the cell.DNA organization from double helix to chromosomes.DNA Epigenetic Mechanisms of Gene ExpressionDNA MethylationDNA methylation mechanism definition.DNA methylation mechanism role.Nucleosome remodelingNucleosome remodeling mechanism definition.Nucleosome remodeling mechanism role.Histone modificationsHistone modifications mechanism definition.Histone modifications mechanism role.Non-coding RNAsNon-coding RNAs mechanism definition.Non-coding RNAs mechanism role.DNA replicationThe central dogmaThe central dogma definition.DNA replication introduction.Origin of replicationOrigin of replication process in eukaryotes.DNA Replication Enzymes – Part 1DNA helicase.Single-strand binding protein.DNA Replication Enzymes – Part 2RNA primase.DNA polymerase I, II, and III.DNA Replication Enzymes – Part 3DNA ligase.Topoisomerase.Synthesizing a New DNA StrandsSynthesizing the leading strand.Synthesizing the lagging strand.DNA damage repairDNA Damage Repair Mechanisms – Part 1Mismatch repair mechanism.Base excision repair mechanism .DNA Damage Repair Mechanisms – Part 2Homologous recombination & Non homologous recombination mechanisms.Nucleotide excision repair mechanism.Direct damage reversal mechanism.DNA TranscriptionDNA Transcription Process and StepsDNA transcription.Initiation stage.Elongation stage.Termination stage.Post-Transcriptional ModificationsRNA ProcessingRNA processing mechanism.Initiation of Translation and mRNA Degradationinitiation of translation and mRNA degradation mechanisms.Protein Processing and DegradationProtein processing and degradation mechanisms.DNA TranslationDNA Translation Process and StepsDNA Translation.Initiation stage.Elongation stage.Termination stage.Post-Translational ModificationsProtein Folding and Targeting Polypeptides to Specific LocationsProtein Folding.Targeting polypeptides to Specific Locations.Gene regulationGene regulation control.Transcription factors.Enhancers.The TATA box.Exons and introns

Overview
Section 1: Introduction

Lecture 1 Introduction to the course

Lecture 2 DNA is the genetic material Experiments

Lecture 3 DNA structure and function

Lecture 4 DNA organization inside the cell.

Section 2: DNA Epigenetic Mechanisms of Gene Expression

Lecture 5 DNA Methylation

Lecture 6 Nucleosome remodeling

Lecture 7 Histone modifications

Lecture 8 Non coding RNAs mechanisms

Section 3: DNA replication

Lecture 9 The central dogma

Lecture 10 Origin of replication

Lecture 11 DNA Replication Enzymes – Part 1

Lecture 12 DNA Replication Enzymes – Part 2

Lecture 13 DNA Replication Enzymes – Part 3

Lecture 14 Synthesizing a New DNA Strands

Section 4: DNA damage repair

Lecture 15 DNA Damage Repair Mechanisms – Part 1

Lecture 16 DNA Damage Repair Mechanisms – Part 2

Section 5: DNA Transcription

Lecture 17 DNA Transcription Process and Steps

Section 6: Post-Transcriptional Modifications

Lecture 18 RNA Processing

Lecture 19 Initiation of Translation and mRNA Degradation

Section 7: DNA Translation

Lecture 20 DNA Translation Process and Steps

Section 8: Post-Translational Modifications

Lecture 21 Protein Folding and Targeting Polypeptides to Specific Locations

Lecture 22 Protein Processing and Degradation

Section 9: Gene regulation

Lecture 23 Mechanism of Gene Regulation

Students who are interested in biology, and molecular biology at any level.